Evaluation of Serum Biochemical Parameters of Cirrhinus Mrigala Under Acute Exposure of Arsenic

Abstract

Arsenic, a  toxicant of fresh water habitat have damaging effects in fish. The present study was carried out to evaluate the lethal toxicity of As₂O₃ to Cirrhinus mrigala at different exposure durations comprises 24-hour, 48-hour, 72-hour and 96-hour along with the analysis of different serum biochemical parameters. Different constituents of serum such sodium, potassium, Chlorine, urea, protein, glucose, albumin, alanine aminotransferase and aspartate aminotransferase were analyzed in control and arsenic exposed groups. The results depicted prominent variations among all parameters of serum under acute exposure of arsenic trioxide. The levels of Na⁺, Cl^- and albumin were recorded lower at all exposure durations of arsenic as compared to the control group. However, the levels of K⁺, total protein, urea, total glucose, AST and ALT were recorded higher in all arsenic exposed fish groups in comparison to control group. The results indicated that arsenic trioxide has adverse effect on serum biochemical parameters and these serum constituents could be used as bioindicators to assess the toxicity caused by As₂O₃ and thus they help in assessing the health status of fish.